Latest Injury Updates Impacting Tennessee Titans Roster

As the Tennessee Titans navigate the final stretch of the 2025 NFL regular season—currently clinging to a 6-5 record and a wild-card spot—recent injury updates have introduced uncertainty to their roster, forcing adjustments on both offense and defense. Over the past two weeks, the Titans have seen three key contributors land on the injury report: running back Derrick Henry (rib contusion), left tackle Andre Dillard (knee sprain), and linebacker Harold Landry III (hamstring tightness). While none of the injuries are considered season-ending, their potential absences or limited roles in upcoming games—including a critical Week 13 divisional matchup against the Jacksonville Jaguars—threaten to disrupt the Titans’ momentum. For a team relying on consistency to stay in the playoff hunt, these injury developments have become a top priority for coaches, trainers, and front-office staff. Latest Injury Updates Impacting Tennessee Titans Roster isn’t just about who’s hurt; it’s about how the Titans adapt to keep their playoff hopes alive.

The most impactful injury update centers on running back Derrick Henry, who suffered a rib contusion in the Titans’ Week 11 win over the New Orleans Saints. Henry, the team’s all-time leading rusher and offensive focal point, left the game in the third quarter after taking a hard hit while carrying the ball and did not return. Initial tests ruled out a fracture, but the Titans placed him on the “questionable” list for Week 12, with head coach Mike Vrabel noting that Henry’s availability would depend on his ability to tolerate contact in practice. Henry’s absence would be a significant blow: he’s rushed for 892 yards and 7 touchdowns this season, accounting for 35% of the Titans’ total rushing yards. Backup running back Tyjae Spears—who has 345 yards and 2 touchdowns in a reserve role—would likely step into the starting spot if Henry is sidelined, but Spears lacks Henry’s size (247 pounds) and ability to break tackles in short-yardage situations. “Derrick is irreplaceable in terms of what he brings to our offense,” offensive coordinator Tim Kelly said. “We have a plan for Tyjae, but we’re hopeful Derrick can play—he’s our engine.” Latest Injury Updates Impacting Tennessee Titans Roster highlights how Henry’s health directly shapes the Titans’ offensive identity.

On the offensive line, left tackle Andre Dillard’s knee sprain—sustained during a Week 11 practice—has created a gap at a critical position. Dillard, who signed a three-year contract with the Titans in free agency to replace the retired Taylor Lewan, has started all 11 games this season, anchoring the left side of the line and protecting quarterback Will Levis’ blind side. Initial MRI results showed a Grade 2 sprain, which typically requires 2-3 weeks of recovery, making Dillard doubtful for Week 12 and questionable for Week 13. To fill the void, the Titans plan to elevate backup tackle Jamarco Jones from the practice squad to the active roster. Jones, a sixth-year veteran, has limited starting experience (12 career starts) and has primarily played right tackle in his career, meaning he’ll need to adjust to the left side—a switch that often takes time to master. The Titans’ offensive line already ranks 22nd in the NFL in sacks allowed (28), and Dillard’s absence could expose Levis to more pressure, especially against pass-rushing threats like the Jaguars’ Josh Allen. “Andre’s consistency on the left side has been key for us,” Vrabel said. “Jamarco has worked hard, but this is a big opportunity for him to step up.” Latest Injury Updates Impacting Tennessee Titans Roster underscores the ripple effect of offensive line injuries on quarterback protection and run blocking.

For the Tennessee Titans, the injury to linebacker Harold Landry III adds another layer of complexity to their defensive game plan. Landry, who leads the team with 6.5 sacks and 14 quarterback hits, reported hamstring tightness after Week 11 practice and was held out of the Saints game as a precaution. While an MRI showed no tear, the Titans are taking a cautious approach, listing him as “probable” for Week 12 but limiting his reps in practice to avoid worsening the issue. Landry’s role as the Titans’ top edge rusher is critical: he’s responsible for disrupting opposing quarterbacks and setting the edge in run defense, tasks that would fall to backup linebacker Arden Key if Landry is limited. Key has 2 sacks this season but lacks Landry’s speed off the edge, which could allow opposing left tackles to focus more on the Titans’ interior pass rush. “Harold’s ability to get to the quarterback changes everything for our defense,” defensive coordinator Shane Bowen said. “We need him at full strength, so we’re not going to rush him back.” The Tennessee Titans also face depth concerns at linebacker beyond Landry: backup Monty Rice is still recovering from an ankle injury, leaving the team with only four healthy linebackers on the roster. Latest Injury Updates Impacting Tennessee Titans Roster shows how defensive injuries can weaken multiple phases of the unit.

The Tennessee Titans’ front office has responded to these injuries with strategic roster moves, aiming to maintain depth while keeping salary-cap flexibility. To replace Dillard on the active roster, the Titans signed Jones from the practice squad and waived rookie tight end Josh Whyle—who had been inactive for all 11 games—to clear a spot. They also added running back Jonathan Ward to the practice squad as insurance for Henry, giving them a third healthy running back if needed. These moves reflect the Titans’ focus on short-term fixes without sacrificing long-term assets, a balance Vrabel has emphasized all season. “We have to be smart about how we manage our roster,” general manager Ran Carthon said. “We need to win now, but we also can’t burn bridges for the future.” The Tennessee Titans have also leaned on their medical staff to accelerate recoveries: Henry has been participating in daily rehabilitation sessions, including ultrasound therapy for his ribs, while Dillard has been using a knee brace in practice to stabilize the joint. These efforts highlight the Titans’ commitment to getting key players back on the field as soon as possible. Latest Injury Updates Impacting Tennessee Titans Roster demonstrates how roster management and medical care work in tandem to mitigate injury risks.

Looking ahead, the Tennessee Titans’ ability to navigate these injuries will likely define their playoff fate. If Henry and Landry can return to full strength for Week 13’s game against the Jaguars—a matchup that could decide the AFC South lead—the Titans stand a strong chance of extending their winning streak. However, if injuries force them to rely on backups for multiple weeks, their offense may struggle to sustain drives, and their defense could struggle to contain top-tier offenses. Vrabel has emphasized resilience in team meetings, reminding players that injuries are part of the NFL and that everyone must step up. “We don’t make excuses—we adapt,” Vrabel said. “Whether it’s Tyjae at running back, Jamarco at tackle, or Arden at linebacker, we have confidence in the guys behind our starters.” For the Tennessee Titans, these injury updates are a test of depth, preparation, and mental toughness—qualities they’ll need in abundance to make a deep playoff run. Latest Injury Updates Impacting Tennessee Titans Roster is a reminder that in the NFL, success often depends not just on talent, but on how a team responds to adversity.